Pergamon or Pergamum was an ancient Greek city, in Mysia, north-western Anatolia, 16 miles from the Aegean Sea, located on a promontory on the north side of the river Caicus (modern day Bakırçay), that became an important kingdom during the Hellenistic period, under the Attalid dynasty.

Pergamon's library on the Acropolis (the ancient Library of Pergamum) is the second best in the ancient Greek civilisation. When the Ptolemies stopped exporting papyrus, partly because of competitors and partly because of shortages, the Pergamenes invented a new substance to use in codices, called pergaminus or pergamena (parchment) after the city. This was made of fine calf skin, a predecessor of vellum. The library at Pergamom was believed to contain 200,000 volumes, which Mark Antony later gave to Cleopatra as a wedding present. The lower part of the Acropolis has the following structures:

• the Upper Gymnasium
• the Middle Gymnasium
• the Lower Gymnasium
• the Temple of Demeter
• the Sanctuary of Hera
• the House of Attalus
• the Lower Agora and
• the Gate of Eumenes

Three kilometers south of the Acropolis was the Sanctuary of Asclepius (also known as the Asclepeion), the god of healing. In this place people with health problems could bathe in the water of the sacred spring, and in the patients' dreams Asclepius would appear in a vision to tell them how to cure their illness. Archeology has found lots of gifts and dedications that people would make afterwards, such as small terracotta body parts, no doubt representing what had been healed. Notable extant structures in the Asclepeion include:

• the Roman theater
• the North Stoa
• the South Stoa
• the Temple of Asclepius
• a circular treatment center (sometimes known as the Temple of Telesphorus)
• a healing spring
• an underground passageway
• a library
• the Via Tecta (or the Sacred Way, which is a colonnaded street leading to the sanctuary) and
• a propylon.